Bio-Chemistry

About the Department

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The Department of Biochemistry, the first independent Department in Government College in our State, was established in 1980 with UG course. The Department now imparts teaching to leading B.Sc., shift-II from 2007, M.Sc., from 1988-1989 and Research, M.Phil.,from1997-1998 and Ph.D from 2006-2007.Biochemistry Department has well qualified faculty, most of whom are actively engaged in teaching and research in goal oriented fields of Biochemistry e.g. Biochemical Toxicology,Biotechnology, Clinical Biochemistry, Environmental Biochemistry, Enzymology, Hematology, Immunochemistry, Marine Biochemistry, Molecular Biology, Nutrition, etc. The Department has historically done some well cited work in Heat Shock Proteins, Autism and Oral Cancer Biology.

Publications in peer reviewed journals by the faculty are more than 250. The secret of success of this Department lies in the academic environment and close ties between teachers and nearly 260 students. While one enjoys such flexibility, a rigid discipline is maintained as far as the classes and projects are undertaken. This makes the Department efficient as a research institute minus the official rigidity there in. Following its tradition, the present students in this Department are exposed to most of the emerging areas in Biochemistry.

The Department library is the one our students visit every day because it is always accessible, and has what they need stacked with over 1500 books and 20 journals.Presently a number of Research Projects are carried out by Dr.A.Geetha (UGC Award) and Dr.E.Padmini (Best Teacher and Best Scientist Awards by the State) faculty members of this Department. There has been some important work in the fields of Stress induced gene expression and the role of reactive oxygen species with more than one crore funds from UGC, ICMR, DST and NTRF. Diverse it may sound, but there is ample scope for integration of the different projects. A correlation between oxidative and Nitrosative stress can lead to better understanding of the molecular pathology of stress and disease. The funds sought for in the project are primarily to cater the students to some emerging areas in Biochemistry and to integrate the current research projects in the manner referred above.

Staff Profile

S.NoNameQualificationDesignationExperienceResearch Guidance*
UGPGM.PhilPh.D
1 Dr. E.Padmini M.Sc., M.Phil., Ph.D.,Associate Professor and Head262622
2Dr. K.A. Fathima M.Sc., M.Phil, Ph.D.,Associate Professor20181-
3Dr. M.Premalatha M.Sc., M.Phil, Ph.D.,Associate Professor26181-
4Dr. K.Vijayalakshmi M.Sc., Ph.D.Associate Professor201811
5Mrs. N.Meenakshi M.Sc., Associate Professor1613--
6Mrs. Chithra BM.Sc.,M.Phil., Assistant professor0505--

Lab / Infrastructure/ Department Library:

The department has separate laboratories for B.Sc., M.Sc., M.Phil, and Ph. D students. The laboratories have basic amenities with a separate cold room to maintain the equipments. The laboratories are well equipped with gas, water and electricity connections. The newly built M.Phil. and Ph.D. laboratory is equipped with basic aminites to fulfil the the needs of research scholars to carry out their research projects. A new animal house is getting ready and the process is likely to be completed.

Bio-Chemistry Lab Photos

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Library

1.Books count = 1512
2.Journal count = 21

Department result:

    No. appearedNo. PassedPass %No.of first classNo. of first class with distinction
2012 – 13UGE.MShift-I362980.5235
Shift-II321444121
PGE.M13118583
 No. appeareNo. PassedPass %No.of first classNo. of first class with distinction
2013 – 14UGE.M Shift-I331751.5172
Shift-II331644131
PGE.M1574752

Achievements of Research Scholars

S.NoName of the StudentName of the Conference/Seminar/WorkshopTitle of the PaperParticulars
1.J. DayanaNational Conference “Nascent Technologies in Biomedical, Electrical Engineering and Communications” NT-BEECOM’12 organised by Department of Electronics and Communication in Vel tech Multi Tech Dr.Rangarajan Dr.Sakunthala Engineering College, Avadi, Chennai(August 6th 2012)Phytochemical analysis of the bark extract of Terminalia arjuna and its Cardio protective effect Second Prize
2.M.D.Lakshmi PriyaNational Conference on “The Role of Free Radicals in Health and Diseases”. Department of Biochemistry, University of Madras, Guindy Campus, Chennai. 27.1.2012- 28.1. 2012“Role of Oxidative Stress in the patho physiology of autism-A biochemical study”.Awarded First Prize for Paper Presentation
3.R. ArunaNational Conference on Herbal Medicine. Frontier Mediville (A unit of Frontier Lifeline Hospital and Dr. K.M. Cherian Heart Foundation) Elavoor, Gummudupoondi Taluk, Tamil Nadu.Rutin modulates the expression of master switches of NLRP3 inflammasome in rats induced with pancreatitis.Awarded First Prize for Best Paper Presentation
4.P. SugunaBiotech Fest “Biozone 2013” Department of Biotechnology, Dr.M.G.R. Educational and Research Institute. Chennai. Effect of thymoquinone on the expression of C and N-terminal domains of ASC complex of NLRP3 inflammasomes in pancreas –
A study in albino Wistar rats subjected to experimental pancreatitis.
Awarded First Prize for Paper Presentation
5.V. SuganyaSecond National Seminar on “Recent/biotechnology/perspective in Diseases Diagnosis and Therapy- Proteins in Proteomics, genes in genomics, Mediclone Academy of Biomedical Research Centre, Chennai. 18.2.2012 to 19.2.2012“Identification of new diagnostic markers for chronic pancreatitis by serum proteome analysis”Awarded First Prize for paper presentation
6.V. SuganyaNational Symposium on Emerging Horizons in Biotechnology – Challenges and Prospects, Department of Biochemistry, Alpha arts and science college,Chennai.20.09.12- 21.09.12.“Haptoglobin, an acute phase reactant as a marker for Chronic Pancreatitis – Evidence from Serum Proteome Analysis”. Awarded Second Prize for paper presentation
7.V. SuganyaNational Conference on Current Research Perspectives in Biotechnology, Healthcare & Environment.
Department of Biotechnology, Dr.M.G.R. Educational and Reseearch Institute. Chennai
A Novel Serum Protein Marker For Chronic Pancreatitis – Evidence From Proteome AnalysisAwarded First Prize for poster presentation
8.P. MonikaInternational conference on bioactive phytochemicals and therapeutics. Department of Biochemistry & Biotechnology in Annamalai University, Annamalainagar.Effect of Persea americana (Avocado) fruit extract on the level of adiponectin and blood lipids in rats fed with high fat dietTravel grant award
9.Lavanya DInternational conference on Bioengineering (ICBE- 2013), Rajalakshmi Engineering College, Chennai January 2- 4, 2012.Effect of black tea and mint tea on the expression of HSP70 in preeclamptic placental explants.Best Paper presentation
10.Parimala PNational conference on ecology and conservation, St. Johns College, Palayampkottai, Tirunelveli, December 12th and 13th.Cytoprotective role of Heme oxygenase 1 in polluted fish adipocytes.Best paper presentation

Seminar / Workshop / Conferences Organized

S.NoDateTitleResource Person
1.2012-13Inauguration of Biochemistry association meetingA special lecture on “Molecular markers in herbal drug discovery and development” was delivered by Dr. A. Hannah Rachel Vasanthi, Assistant Professor, Department of Biotechnology, and Pondicherry University.
2012-13Intra departmental competitions were held for UG studentsI UG : Display of posters, II UG: Display of models, III UG : Paper presentation
22013-14Intra departmental competitions were held for UG studentsI UG: Display of posters on Environmental science, II UG: Quiz competition on Nutritional Biochemistry and Cell Biology.
2013-14Inauguration of Biochemistry association meetingA special lecture on “Role of clinical Biochemistry and laboratory practices in health care management” was delivered by Dr. R Arivazhagan, Professor and Head, Department of Biochemistry, Cancer Institute, Chennai.
2013-14National Seminar on “Prospects of phytonutrients in human welfare” 1. Dr. D. Sakthisekaran, Professor and Head, Department of Medical Biochemistry, Taramani campus, University of Madras.
2. Dr. C. V. Anuradha, Professor, Department of Biochemistry and Biotechnology, Annamalai University.
3. Dr. K. Sadasivam Pillai, Deputy managing Director, Life Sciences services, Frontier life line pvt Ltd.
4. Dr. Rukmani Rajagopalan, Assistant Professor, managing Director, Life Sciences services, Frontier life line pvt Ltd.
4. Dr. Rukmani Rajagopalan, Assistant Professor, Department of Biochemistry and Molecular Biology, Pondicherry University delivered special lecture Department of Biochemistry and Molecular Biology, Pondicherry University delivered special lecture

Faculty Publications

S.NoNameTitleJournalVol No/Issue No/Page No
1Yamini Chandramohan, Chetenchery Somasundaram Parameswari.Therapeutic efficacy of naringin on cyclosporine (A) induced nephrotoxicity in rats: Involvement of hemeoxygenase-1 Pharmacological Reports2013, 65, 13361344
2M.Premalatha, Dr.C.S.Parameswari.Effect of chrysin on nephroprotective and antioxidant status in streptozotocin induced diabetic nephropathy rats. Abstract published Journal of Pharmacy Research May2013, Vol. 1 Issue 5,484-489.
3.K.A.Fathima, Dr.C.S.Parameswari.Nephroprotective effect of Eupalitin-3-0-β-galactopyranoside in Koi carp(Cyprinus carpio)nternational Journal of Pharmacy ResearchMay 2012,5(5), 2590-2592
4.VasanthiP,
Parameswari CS.
Arjunolic acid attneautes cyclosporine induced nephrotoxicity-mitochondrial study, Journal of Pharmacy Research2012,5(7),3729-3733
5.Dayana.J.,
Parameswari C S.
Emerging Novel Phytochemicals as Immunosuppressants-Review, Journal of Advanced Pharmaceutical ResearchVolume: 4(1), 33-45, March 2013
6.Aruna R, Geetha A, Suguna P.Rutin modulates ethanol and high fat diet - induced inflammatory changes in pancreas – A dose response study in rats. Rutin modulates ethanol and high fat diet - induced inflammatory changes in pancreas – A dose response study in rats. Rutin modulates ethanol and high fat diet - induced inflammatory changes in pancreas – A dose response study in rats. International Journal of Pharmacy and Pharmaceutical Sciences2012; 4(4), 409-414
7.Geetha A.
Megala J,
 
Antiulcerogenic activity of hydroalcoholic fruit extract of Pithecellobium dulce in different experimental ulcer models in rats. Journal of Ethnopharmacology
2012; 142:415-421.
8.Saranya P, Geetha A.A study on the gastroprotective effect of Andrographis paniculata and andrographolide in rats subjected to pylorus ligation.
Journal of Pharmacy Research2012; 5: 787-79
9.
Suganya V, Geetha A, Satish D.Haptoglobin, an acute phase reactant as marker for chronic pancreatitis – evidence from serum proteome analysis.Free Radicals and Antioxidants2012; 2: 12-18
10Geetha A.
Megala J,
Acute and sub-acute toxicity study of hydroalcoholic fruit extract of Pithecellobium dulce.Natural Product Research2012; 26:1167-1171
11.Arumugam G
Vasuki R, Hari R,
 Pandian S,.
Hepatoprotective action of ethanolic extracts of Eclipta alba and Piper longum linn and their combination on CCL4 induced hepatoxicity in rats. International Journal of Pharmacy and Pharmaceutical Sciences2012; 4(1), 455-459
12.Padmini E,
Uthra V and Lavanya. S
Mechanism of JNK signal regulation by placental HSP70 and HSP90 in endothelial Cell during preeclampsia Toxicology mechanism and methods22(5):367-74, 2012.
13.Padmini E and V. Uthra,Role of Ureaplasma urealyticum in altering endothelial metal concentration during preeclampsia, Placenta33: 304-311, 2012.
14.Padmini E, B. Vijaya Geetha, 2012.Mitochondrial HSP70 cognate mediated differential expression of JNK1/2 in the pollution stressed grey mullets, Mugil cephalus. Fish Physiology and Biochemistry38(5):1257-71, 2012
15.Padmini E, Uthra V, Lavanya SEffect of HSP 70 and 90 in modulation of JNK, ERK expression in preeclamptic placental endothelial cell. Cell Biochemistry and Biophysic64(3):187-95, 2012.
16.Padmini E,
Lavanya. S
Effect of mint tea HSP mediated survival mechanism on preeclamptic endothelial cell. International Journal of Pharmaceutical and Biological Research3(4): 1-11, 2012.
17.Padmini E, Lavanya D, Uthra VIn-vitro studies on heme oxygenase-2 and oxidative stress in preeclamptic placental explants. Journal of Pharmacy Research5(4), 2107-2113, 2012.
18.Padmini E, Lavanya D, Tharani J, Lavanya STea and Mint Extracts Modulate the HSP70 Expression in Preeclamptic Placental Explant. Journal of Applied Pharmaceutical Science02 (08): 128-133, 2012
19.Inbathamizh L and Padmini E.Gas Chromatography-Mass Spectrometric analyses of methanol extract of Moringa oleifera flowers. International Journal of Chemical and Analytical Science3(5): 1394-1397, 2012.
20.Inbathamizh L and Padmini E, 2012.In silico Studies On the Inhibitory Effects of Calcitriol and 5, 'Dithiobis -2-Nitrobenzoic Acid on Human Glucosaminyl N-Acetyl Transferase 1 Activity. Asian Journal of Experimental Biological Sciences3(1):14-21.
21.Inbathamizh L and Padmini E, 2012.Ab initio Structure Prediction of Cellular Prostatic Acid Phosphatase and its Interactions with Anti-Cancer Ligands. Journal of Pharmacy Research5(7): 3892-3896.
22.Inbathamizh L and Padmini E, 2012.In silico Studies On the Inhibitory Effects of Calcitriol and 5, 'Dithiobis -2-Nitrobenzoic Acid on Human Glucosaminyl N-Acetyl Transferase 1 Activity. Sci. Asian J. Exp. Biol.3(1):14-21, 2012.
23.K.A.Fathima, Dr.C.S.ParameswariNephroproctecive effect of eupalitin-3-0-β-D-Galacto pyranoside in koicarp (Cyprinus carpio)International journal of pharmacy Research.2012. Vol:5(5) 2590-2592
24.M.Premalatha., Dr.C.S.ParameswariRenoprotective effect of chrysin in streptozotocin induced diabetic nephropathy in ratsInternational journal of pharmacy and pharmaceutical sciences.2012 vol:4 suppl:2
25.Premalatha, M.; Parameswari, C. SEffect of chrysin on nephroprotective and antioxidant status in streptozotocin induced diabetic nephropathy in rats International journal of pharmacy Research2013 vol:1, Issue:5
26.K.Vijayalaksmi & J.SangeethaPhytochemical evaluation of chromatographic finger printing profile rind of Ganesh verity of Punica Granatum Linn.International Journal Of Pharma And Bioscience”2012 Vol3 329-337
27.P.Ramya, S.Seema & K.VijayalaksmiImpact of hydroalcoholic extract of Cyprous Rotuder on glucose- induced Cataract -An invitro study ”Impact of hydroalcoholic extract of Cyprous Rotuder on glucose- induced Cataract -An invitro study ” International Journal Of Pharmacy And Biological Science”
28.S.Seema & K.Vijayalakshmi.GC-MS analysis of Phytochemicals in Cyamposis tetragonolobus fruit and Cyperus rotundus rhizomeInternational journal of Pharmacognacy Phytochemical research”2012, 3(4): 105-109
29.Jananie. RK, Priya.V& Vijayalakshmi. K.GC/MS determination of bioactive components of Pleurotus ostreatus. International research journal of pharmacy”2012, 3(3):150-151
30.Vijayakashmi K & S.SeemaK Antimicrobial activity of Cyperus rotundus and Cyamopsis tetragonolobus – an invitro studyInt. Journal of Pharmaceutical Research and developmen2012, 4(7):137-141
31
H.Sumathi, S.Sathiya; V.Ranju; J.Sangeetha; T.Sadhana; K.Vijayalakshmi; C.Saravana Babu;Relative antioxidant and cytotoxic activity of Ixora cocinea.” “Journal Of Pharmacy Research”2012 1403-1408
32.H.Sumathi, Sangeetha .J & K.Vijalakshmi.Anticancer activity of Punica Granetum rind extract against human lung cancer cell line.”“Asian Journal Of Pharmacological And Clinical Research”2012 Vol5 205-209
33.K.J.Uma devi, V.Vanitha & K.Vijayalakshmi.Physiochemical & phytochemical screening and profiling of secondary metabolites of Annona squamosa leaf extract.“World Journal Of Pharmaceutical Research”2012 Vol 1 1-22
34.K.Vijayalakshmi and Gayathri Gunala.Impact of radiotherapy on oxidative stress in neutrophil of cervical cancer patient” “Asian journal of pharmaceutical and clinical research”2012 vol 2 320-331
35.Gayathri Gunalan A.Saraswathy & K.Vijayalakshmi HPTLC finger printing profile of Bauhinia variegates Linn. Leaves “Asian Pacific journal of tropical disease”2012 21-25.
36.Seema surendran and K.VijayalakshmiSeema surendran and K.Vijayalakshmi. Effect of tamoxifen on mitochondria- An invitro study” “American journal pharmtech research”2012 Vol 2 471-482
37.Jananie. RK, Priya.V & K.Vijayalakshmi.GC/MS Analysis of Bioactivity component of Agaricea Bispor“Asian journal of Pharmaceutical and clinical research”2012,5(2): 168-169
38.Jananie. RK, Priya.V& K.Vijayalakshmi. Secondary metabolites of Cynodon dactylon as an antagonist to angiotensin II type1 receptor: Novel in silico drug targeting approach for diabetic retinopathy“Journal of pharmacology & pharmacotherapeutics”2012, 3:20-25
39.Jananie. RK, Priya.V& K.Vijayalakshmi.Secondary metabolites of Cynodon dactylon as an antagonist to angiotensin II type1 receptor: Novel in silico drug targeting approach for diabetic retinopathyAmerican journal of pharmatech research.2012, 2(1); 377-388
40.Sangeetha, J; K.Vijayalakshmi.Antioxidant status and radical scavenging activity of ganesh variety of the Punica granatum rind extracts. World journal of pharmacy and pharmaceutical science2012, 1(2):799-809
41.Jayasree.S, N.Ramesh, K.Vijayalakshmi & Viridi VinniAnalysis of diabetic retinopathy biomarker VEGF gene by computational approachesJournal of Biochemical Technology2012 4(1): 565-567
S.NoNameTitleJournalVol No/Issue No/Page No
1.Yamini Chandramohan, Chetenchery Somasundaram Parameswari.,Naringin ameliorates renal impairment on cyclosporine (a) - induced nephrotoxicity in rats: involvement of in os. International Journal of Pharma & Bio Sciences.Jul-Sep2013, Vol. 4 Issue 3
2.Premalatha M, Parameswari CSEffect of chrysin on nephroprotective and antioxidant status of streptozotocin induced diabetic nephropathy rats.Journal of Pharmacy ResearchMay 2013, Vol 1, Issue 5
3.Yamini Chandramohan, Chetenchery Somasundaram Parameswari.Therepeutic efficacy on naringin on cyclosporine (A) induced nephrotoxicity rats: involvement of hemeoxygenase-1.Pharmacological Reports2013,65, 1336-1344
4.Karvannan Kanchana, CS ParameswariProtective effect of phyllanthus niruri against cyclosporineA induced nephrotoxicity in rats.,Comparative clinical pathology Sep 2013, `vol 22, issue 5, 885-893.
5.P Vasanthi, CS ParameswariAqueous extract of terminalia arjuna prevents cyclosporine induced Renal disorder,Comparative clinical pathologyMay 2014, vol 23, issue 3, 583-588.
6.Ravikumar Aruna, Arumugam Geetha, Periyanayagam SugunaRutin modulates ASC expression in NLRP3 inflammasome: a study in alcohol and cerulein-induced rat modal of pancreatitis. [In Press]Molecular and Cellular Biochemistr2014
7.Arumugam Geetha,Marimuthu ,Amutha, Mariappan Amutha, Padmanabhan Monika. Determination of secondary metabolites, LD50 value and antioxidant activity of seed extract of Cucurbita pepo Linn.Asian Journal Of Pharmaceutical And Clinical Research.7(3), 2014, 173-177.
8.Arumugam Geetha, Mariappan Amutha, Marimuthu AmuthaA pilot study on the determination of antioxidant potential and letal dosage of hydro alcoholic fruit extract of Terminalia chebula. International journal of pharmacy and pharmaceutical sciences6(6);2014;346-351
9.Padmanabhan Monika, Arumugam Geetha.Effect of Persea americana (avocado) fruit extract on the level of expression of adiponectin and PPAR-γ in rats subjected to experimental hyperlipidemia and obesity. [In press]Journal of complementary and integrative medicine2014. 11(2):107-19
10.Periyanayagam Suguna, Arumugam Geetha, Ravikumar Aruna & Ganesan Vijaiyan Siva.The modulating effect of methanolic seed extract of Nigella sativa on ethanol and high fat diet induced pancreatic injury in rats.[In Press]International journal of pharmacy and pharmaceutical sciences6(1);2014, 358-363.
11.Ravikumar Aruna, Arumugam Geetha, Periyanayagam Suguna & Vijayashankar Suganya.Rutin rich Emblica officinalis fruit extract ameliorates inflammation in the pancreas of rats subjected to alcohol and cerulein administration.[In Press]Journal of complementary and integrative medicine.2014;11(1).
12.Periyanayagam Suguna, Arumugam Geetha, Ravikumar Aruna & Ganesan Vijaiyan Siva.Thymoquinone rich Nigella sativa seed extract modulate the activity of ASC protein complex in rats subjected to experimental pancreatitis.[In Press]Biomedicine and preventive nutrition.2013
13.Ravikumar Aruna, Arumugam Geetha, Periyanayagam Suguna.Levels of expression of CARD and PYD domains of ASC complex in the pancreas of rats subjected to experimental pancreatitis – Influence of rutin administration.Human and Experimenatal toxicology2013;33(9); 940-948
14.Suguna P, Geetha A, Aruna R, Siva GV.Effect of thymoquinone on ethanol and high fat diet induced chronic pancreatitis-a dose response study in rats.Indian Journal of Experimental Biology2013; 51(4) 292-302
15.Sam Annie Jeyachristy, Geetha Arumugam, Surendran Rajagopal,
Jeevan Kumar Subburayan, Arulprakash Sarangapani.
Influence of nitric oxide and cGMP on agonist-induced Platelet adhesion – an in vitro study in platelets isolated from patients with liver cirrhosisJournal of Medical Biochemistry 2013; 32: 59-67
16.Priya MDL, Geetha A, Suganya,V, Sujatha S.Abnormal circadian rhythm and cortisol excretion in autistic children: A clinical study.Croatian Medical Journa2013; 54(1), 33-41
17.Antony FC, Geetha A, Narayanan DC. Effect of Galangin on ethanol and cerulein induced inflammatory changes in pancreas: A biochemical study in rat model.International Journal of Pharmacy and Pharmaceutical Sciences2013; 5(3), 858-8
18.Padmini E, Tharani J, Uthra V and Sheila LPreeclamptic cord blood hemolysis and the effect of Monascus purpureus and Saccharomyces cerevisiae in modulating preeclamptic stress; Impact factor: 0.345 Bratislava medical journal- Bratisl Lek Listy114 (9)508-513, 2013.
19.Padmini E, Tharani J, Lavanya D.Differential Expression of HSP90α and Heme oxygenase in cord blood RBC during preeclampsia. Toxicology mechanism and methods23(2): 113-119(7), 2013.
20.Inbathamizh L and Padmini EEffect of geographical properties on the phytochemical composition and antioxidant potential of Moringa oleifera flowers. Journal of Pharmacy Research1(3): 239-247. 2013.
21.Inbathamizh L and Padmini EMoringa oleifera flower compounds as potent ligands to drug targets in PC3 cell lines – an in silico analysis., Impact factor: nilInternational Journal of Pharmacy and Pharmaceutical Sciences5(4): 377-383. 2013.
22.Inbathamizh L and Padmini EMolecular dynamics simulations of native and mutant glucosaminyl (n-acetyl) transferase 1 prove their biochemical variations. International Journal of Pharmacy and Pharmaceutical Science5(4): 511-516. 2013.
23.Inbathamizh L and Padmini EEvaluation of growth inhibitory potential of Moringa oleifera flowers on PC3 cell lines. Impact factor: nilAsian Journal of Pharmaceutical and Clinical Research6(4): 60-64. 2013.
24.Inbathamizh L and Padmini EQuinic acid as a potent drug candidate for prostate cancer – a comparative pharmacokinetic approach.Asian Journal of Pharmaceutical and Clinical Research 6(4): 106-112, 2013
25.Padmini E, Parimala P,Activation of HO-1 downregulates TSH in stressed fish adipocytes.Indo-American Journal of Life Sciences and Biotechnology2014, 2(1): 32-46.
26.Padmini E, Lavanya D,Studies on the modulation of hypoxia inducible factor-1α, heme oxygenase-1 and tumor necrosis factor-α expression in preeclamptic placental explants.International journal of research in chemistry and environment2014, 4(2), 85-92.
27.Padmini E, Tharani JFourier transform infrared spectroscopic study on HSP70 and ERK in fish hepatocytes during pollution induced stress, International journal of research in chemistry and 2014, 4(2): 114-125.
28.Padmini E, Lavanya DDifferential expression of heat shock proteins and inflammatory changes in preeclamptic placental explants, International Journal of Science and Research2014;3(4): 858-864.
29.Padmini E, Meenakshi N, Tharani JChanges in Oxidative Stress and Antioxidant Status in Stressed Fish BrainInternational Journal of Science and Research2014. 3(5): 164-170.
30.
Padmini E, Lavanya DApoptosis signal regulating kinase-1 expression down regulated in preeclamptic placental explants incubate with mint-teaBiomedicine2014; 34(2):171-179.
31.Padmini E, Tharani JHeat shock protein 70 modulates apoptosis signal regulating kinase 1 in stressed hepatocytes of Mugil cephalus,Fish Physiology and Biochemistry“2014 40 (5): 1573-85”
32.Gayathri Gunalan K.Vijayalakshmi & A.SaraswathyQuantitative phytochemical profile of Bauhinia variegata Linn. Leaves.International journal of biological and pharmaceutical research 2013 Vol 4: 907-915
33.D. Hari Priya, K.Nadhiya & K.VijayalakshmiAntioxidant Potential of Cinnamaldehyde – An invitro study.International Journal Of Pharmaceutical Research And Bio-Science 2013 Vol2(5): 270-278
34.A.Khadira Sereen & K.Vijayalakshmi. Antioxidant potential and reducing activity of Sesamol. International Journal Of Pharmaceutical Research And Bio-Science2013, 2(6): 465-474
35.Ashok Kumar K & K.Vijayalakshmi. In vitro antioxidant activity and cytotoxic potential of Punica granatum peel and Vitis vinifera seeds on Hep G2 cell lines. International journal of future biotechnology2013, 2(2): 26-32.
36.Ashok Kumar K & K.Vijayalakshmi. In vitro antimicrobial activity and phytochemical analysis of selected fruit wastes. International Journal of current microbiology and applied sciences, 2013,2(5) :196-204
37.K.Vijayalakshmi, Priya.N, A.Khadira Sereen & Ranjani.RPreliminary phytochemical screening of the fruit rind of Garcinia cambogia and leaves of Bauhinia variegata- A comparative study. International journal of current microbiology and applied sciences 2014, 3(5);1-8
38.Indhumathi.P & K.Vijayalakshmi Comparative study on Physico& Phyto-chemical analysis of Persea Americana & Actinidia deliciosa. International journal of scientific and research publications 2014, 4(5):1-5
39.B.Arirudran, A.Saraswathy & K.Vijayalakshmi. Evaluation of alternative chemotherapeutic agent from Ruellia tuberosa for hepatocellular carcinoma using HepG2 cell lines. International Journal of Biochemistry2014,195; 306-321
40.B.Arirudran, A.Saraswathy & K.Vijayalakshmi.Acute toxicity study of ethanolic extract of Ruellia tuberosa in wistar albino mice. International journal of Biosciences and Technology 2014;7(1);1-4
41.S.Seema & K.Vijayalakshmi. Effect of ethanolic extracts of Cyamopsis tetragolobus and Cyperus rotundus on biochemical parameters of Diabetic cataract induced wistar albino rats. International journal of Pharma and Bio Sciences2014,5(2): 708-717
42.K. Nadhiya & K.VijayakalshmiEvaluation of total phenol,flavonoids contents and invitro antioxidant activity of Benincasa hispida fruit extracts. International journal of Pharmaceutical chemical and biological2014; 4(2).
43.S.Nazareth Arokiyamary & K.Vijayalakshmi.Invitro antioxidant assay &Anticarcinogen effect of Solanum tuberosum in HepG2 cell line. International journal of Biological and pharmaceutical research 2014; 5(1); 78-82.
44.Ranjani.R, Khadira Sereen.A, Priya.N& Vijayalakshmi.KAntioxidant profile of the fruit rind of Garcinia cambogia and leaves of Bauhinia variegata – an invitro investigation, International journal of Pharmaceutical research and Bioscience2014,
3(3): 528-538
45.Hari Priya.D, Nadhiya.K, Rajasree Shrama & K.VijayalakshmiMolecular Docking Analysis of secondary metabolites of Trigonella foenum graceaum and Carica papaya with FTO, An insilico approachInternational Journal of pharmaceutical science review and research2014, (in press)
46.Seema.S & K.VijayalakshmiCyperus rotundus delays diabetic cataract better than Cyamopsis tetragonolobus by regulating polyol pathway and oxidative stress in wistar albino ratsInternational journal of Biochemistry2014 (in press)
47.Hari Priya.D & K.VijayalakshmiThe effect of CA on HDF induced Wister rats – A Preliminary study.International journal of pharmaceutical science research (in press)
48.K. Vijayalakshmi; S.Seema; S.Vadivelan; V.V. Prasanna; JARP.Sarma;Molecular docking of secondary metabolites from Cyperus rotundus and Cyamopsis tetragonolobus against aldose reductase-A novel drug target for diabetic cataract. JPR. BioMedRx, 2013, 1(1):59-67
49.
Gayathri Gunalan K.Vijayalakshmi & A.SaraswathyMolecular profiling of Bauhinia variegata using RAPD. Journal of phytochemistry 2013 114: 226-232
50.K.Nadhiya, D. Hari Priya & K.Vijayalakshmi.Pharmacognostic and Preliminary Phytochemical Analysis of Benincasa Hispida fruit. Asian Journal Of Pharmaceutical And Clinical Research2014, 7(1): 98-101
51.N.Priya & K.VijayalakshmiIC50 value of Hesperidin an Invitro study. The Journal of free radicals and Antioxidants 2014, 140: 271-277
52.B.Arirudran, A.Saraswathy & K.Vijayalakshmi.Impact of Ruellia tuberosa on regulating the levels of lipid peroxidation and antioxidants in DEN induced liver cancer in wistar albino rats.The journal of free radicals and antioxidants, 2014,140;308-317
53.B.Arirudran, A.Saraswathy & K.Vijayalakshmi.Hepato protective activity of ethanolic and ethyl acetate extract of Ruellia Tuberosa L.(whole plant) against N-Nitrosodiethylamine induced liver cancer in wistar albino rats. American journal of pharmatech research2014; 4(3)
54.S.Seema & K.VijayalakshmiCyamopsis tetragonolobus and Cyperus rotundus prevents oxidative stress in Diabetic cataract induced wistar albino rats.World journal of Pharmacy and pharmaceutical sciences2014; 3(3): 2201-2211
55.Ashok Kumar K & K.VijayalakshmiProtective effect of Punica granatum peel and Vitis vinifera seeds on DEN induced oxidative stress and hepatocellular damage in rats.Applied biochemistry and biotechnology2014 (in press)
56.N. MeeenakshiChanges in Oxidative Stress and Antioxidant Status in Stressed Fish BrainInternational Journal of Science and Research (IJSR)“2014 3(5): 164-170”

Minor/Major projects:

S.NoNameTitleSponsored organizationAmount
1.Dr.C.S.ParameswariBiochemical studies on the Immunomodulatory effect of Zingerone in fish model – An Heuristic ApproachTamil Nadu State Council for Higher Education (Minor project-2014 Ongoing)Rs. 1,00,000/-
2.Dr. A. GeethaA clinical proteomic study for the screening of diagnostic markers in urine and serum of autistic children: An attempt to explain the pathophysiology of autismICMR – ad-hoc Project
(Major project-2012-2015)
Rs.21,13,886/-
3.Dr. E. PadminiStudies on the anti-apoptotic function of HSP70, HO-1 and cytochrome P450 in polluted fish hepatocytesUniversity Grants Commission (2012-2015)Rs.13,86,800/-
Studies on the role of tea in modulating heme oxygenase-1 and cytochrome P450 in placental explantsNational Tea Research Foundation (2013- 2015Rs.12,60,760/-
Studies on the metabolic programming and the associated signaling changes in fish adipocytes during hypoxic conditionsDepartment of Science and Technology (2013- 2016)Rs.49,80,000/-